Nature Communications (Jun 2016)

Active diffusion and microtubule-based transport oppose myosin forces to position organelles in cells

  • Congping Lin,
  • Martin Schuster,
  • Sofia Cunha Guimaraes,
  • Peter Ashwin,
  • Michael Schrader,
  • Jeremy Metz,
  • Christian Hacker,
  • Sarah Jane Gurr,
  • Gero Steinberg

DOI
https://doi.org/10.1038/ncomms11814
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 14

Abstract

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The mechanisms underlying the positioning of eukaryotic organelles remain elusive. Here Lin et al. use imaging and a mathematical model to show that microtubule-based transport and active diffusion and actin-based polar drift act together to facilitate even distribution of peroxisomes in filamentous fungi.