Brazilian consensus in muscle-invasive and metastatic urothelial carcinoma

Abstract

Urothelial carcinoma is a frequent worldwide malignancy. Poor survival rates in muscle-invasive and metastatic urothelial carcinoma impose major challenges for management. We conducted a consensus meeting to discuss the optimal treatment for urothelial carcinoma in Brazil, which was developed by a panel of multidisciplinary experts consisting of oncologists, urologists and radiation therapists. This paper provides recommendations for perioperative treatment, metastatic disease management, bone directed therapy and genetic counselling in urothelial carcinoma based on the specialists opinions and was classified according to the level of evidence found in the medical literature according to the Oxford classification. The recommendations were based on the available treatments in Brazil to guide health professionals in the management of urothelial carcinoma in low- and middle- income countries with limited access to therapy.

Keywords

• Urothelial carcinoma
• Bladder cancer
• Cystectomy
• Chemotherapy
• muscle-invasive
• Metastatic urothelial carcinoma
• Upper urinary tract carcinoma
• Carcinoma urotelial
• Câncer de bexiga
• Cistectomia
• Quimioterapia músculo invasiva
• Carcinoma urotelial metastático
• Carcinoma do trato urinário superior