Obesity-related biomarkers underlie a shared genetic architecture between childhood body mass index and childhood asthma

Xikun Han; Zhaozhong Zhu; Qian Xiao; Jun Li; Xiumei Hong; Xiaobin Wang; Kohei Hasegawa; Carlos A. Camargo; Liming Liang

doi:10.1038/s42003-022-04070-9

Communications Biology (Oct 2022)

Obesity-related biomarkers underlie a shared genetic architecture between childhood body mass index and childhood asthma

Xikun Han,
Zhaozhong Zhu,
Qian Xiao,
Jun Li,
Xiumei Hong,
Xiaobin Wang,
Kohei Hasegawa,
Carlos A. Camargo,
Liming Liang

Affiliations

Xikun Han: Department of Epidemiology, Harvard T H Chan School of Public Health
Zhaozhong Zhu: Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School
Qian Xiao: Department of Biostatistics, Harvard T H Chan School of Public Health
Jun Li: Department of Nutrition, Harvard T H Chan School of Public Health
Xiumei Hong: Center on the Early Life Origins of Disease, Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health
Xiaobin Wang: Center on the Early Life Origins of Disease, Department of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health
Kohei Hasegawa: Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School
Carlos A. Camargo: Department of Epidemiology, Harvard T H Chan School of Public Health
Liming Liang: Department of Epidemiology, Harvard T H Chan School of Public Health

DOI: https://doi.org/10.1038/s42003-022-04070-9
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 10

Abstract

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A comprehensive genetic analysis of the relationship between childhood obesity and childhood asthma identifies shared mechanisms and potential mediators linking the two pediatric disorders.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal