Control and Elimination of Extensively Drug-Resistant Acinetobacter baumanii in an Intensive Care Unit

Abstract

We decreased antimicrobial drug consumption in an intensive care unit in Lebanon by changing to colistin monotherapy for extensively drug-resistant Acinetobacter baumanii infections. We saw a 78% decrease of A. baumanii in sputum and near-elimination of blaoxa-23-carrying sequence type 2 clone over the 1-year study. Non–A. baumanii multidrug-resistant infections remained stable.

Keywords

• XDR
• MDR
• Acinetobacter baumanii
• carbapenem
• antimicrobial stewardship
• antimicrobial resistance