RUDN Journal of Medicine (Dec 2017)

CUTANEOUS APPLICATION OF A OF NITROGLYCERIN IN COMPLEX TREATMENT OF DEGENERATIVE-DYSTROPHIC DISEASES OF LARGE JOINTS

  • E A Nazarov,
  • M N Ryabova,
  • A V Vasilieva

DOI
https://doi.org/10.22363/2313-0245-2017-21-3-374-380
Journal volume & issue
Vol. 21, no. 3
pp. 374 – 380

Abstract

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The article presents a preliminary analysis of the application of the new non-invasive method of treatment of degenerative-dystrophic diseases of large joints. The aim of the study was to examine the results of the cutaneous insertion of a nitroglycerin solution at a concentration of 2.5 mg/ml with degenerative diseases of knee and hip joint. Materials and methods. In 9 patients studied results: physical, x-ray studies; testing scales: the Oxford Knee Score, KOOS-WOMAC, Lisholm, Leken, Harris; blood gases; pulse oximetry; capillaroscopy. Results. All patients satisfied with treatment, significant pain re-duction, increase range of motion, rejection of the use of means of additional supports, as evidenced by the data evaluation scales. Indicators of blood gas composition, the data of pulse oximetry, capillaroscopy showing improvements in tissue circulation. Conclusions. Cutaneous application of nitroglycerin in the us used concentration improves blood circulation and, as a consequence, the metabolism in the affected joint that can slow the progression of the disease. Ease of use will allow you to apply a method of treating patients not only in hospital but on an outpatient basis.

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