Advances in understanding and managing atopic dermatitis [version 1; referees: 2 approved]

Abstract

Atopic dermatitis is a chronic, pruritic skin disease characterized by an improperly functioning skin barrier and immune dysregulation. We review proposed atopic dermatitis pathomechanisms, emphasizing how these impact current perspectives on natural history, role of allergic sensitization, and future therapeutic targets.

Keywords

• Allergy & Hypersensitivity
• Atopic Dermatitis & Other Forms of Eczema
• Cellular Microbiology & Pathogenesis
• Dermatologic Pharmacology
• Innate Immunity
• Medical Genetics
• Medical Microbiology
• Musculoskeletal Pharmacology
• Pediatric Skin Diseases (incl. Genetic Diseases)