A retroperitoneal cyst with unusual urinary histogenesis: clinical and immunomorphological characteristics

Abstract

Giovanni Branca1, Antonio Ieni1, Valeria Barresi1, Antonino Versaci21Section of Anatomic Pathology, 2Section of General Surgery, Department of Human Pathology, Azienda Ospedaliera Universitaria “Policlinico G. Martino”, University of Messina, Messina, ItalyAbstract: Primary retroperitoneal cysts are rare benign lesions which often present as an incidental radiological finding and also cause abdominal symptoms. A 47-year-old woman was admitted to the surgery unit because of right-sided abdominal pain. Computed tomographic scan investigation confirmed a circumscribed, oval, dishomogeneous mass in the right anterior pararenal space. The final diagnosis was obtained after laparotomy excision and pathological evaluation. Immunohistochemical profile was characterized by positive expression of epithelial cystic cells for CKAE1/AE3, CK7, CK8, and CK18, with EMA sustaining the diagnosis of a benign retroperitoneal cyst of urinary system origin.Keywords: retroperitoneal cyst, cytokeratins, urinary tract