Subthalamic nucleus stabilizes movements by reducing neural spike variability in monkey basal ganglia

Taku Hasegawa; Satomi Chiken; Kenta Kobayashi; Atsushi Nambu

doi:10.1038/s41467-022-29750-2

Nature Communications (Apr 2022)

Subthalamic nucleus stabilizes movements by reducing neural spike variability in monkey basal ganglia

Taku Hasegawa,
Satomi Chiken,
Kenta Kobayashi,
Atsushi Nambu

Affiliations

Taku Hasegawa: Division of System Neurophysiology, National Institute for Physiological Sciences
Satomi Chiken: Division of System Neurophysiology, National Institute for Physiological Sciences
Kenta Kobayashi: Department of Physiological Sciences, SOKENDAI
Atsushi Nambu: Division of System Neurophysiology, National Institute for Physiological Sciences

DOI: https://doi.org/10.1038/s41467-022-29750-2
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 15

Abstract

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Chemogenetic inactivation of the subthalamic nucleus in monkeys increases spike train variability in the pallidum and prolongs movement time, suggesting its role in stabilizing pallidal spike trains to achieve stable motor control.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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