Bangladesh Journal of Pharmacology (May 2010)

Synthesis of some pyrazolone derivatives from ciprofloxacin and study of their cytotoxicity

  • Hari Pado Devnath,
  • Md. Rabiul Islam

DOI
https://doi.org/10.3329/bjp.v5i1.4693
Journal volume & issue
Vol. 5, no. 1

Abstract

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Three pyrazolone derivativeswith pyrazole ring extensionwere synthesized from ciprofloxacin by treating the parent compound with hydrazine derivatives. All the products have been characterized by IR and 1H-NMR spectral analysis. These derivatives showed potential cytotoxicity against brine shrimp nauplii than the ciprofloxacin.

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