Preoperative intensity-modulated chemoradiation therapy with simultaneous integrated boost in rectal cancer: 2-year follow-up results of phase II study

Abstract

The aim of the study was to investigate the feasibility and safety of experimental fractionation using intensity modulated radiation therapy with a simultaneous integrated boost (IMRT-SIB) to shorten the overall treatment time without dose escalation in preoperative radiochemotherapy of locally advanced rectal cancer.

Keywords

• rectal cancer
• intensity modulated radiation therapy
• simultaneous integrated boost
• preoperative radiochemotherapy
• acute toxicity
• pathologic complete response