Nature Communications (Jul 2018)

Predicting treatment benefit in multiple myeloma through simulation of alternative treatment effects

  • Joske Ubels,
  • Pieter Sonneveld,
  • Erik H. van Beers,
  • Annemiek Broijl,
  • Martin H. van Vliet,
  • Jeroen de Ridder

DOI
https://doi.org/10.1038/s41467-018-05348-5
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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Selection of the right cancer treatment is still a challenge. Here, the authors introduce a framework to analyze treatment benefits, using the idea that patients with similar genetic tumor profiles receiving different treatments can be used to model their responses to the alternative treatment.