Olfactory inputs modulate respiration-related rhythmic activity in the prefrontal cortex and freezing behavior

Andrew H. Moberly; Mary Schreck; Janardhan P. Bhattarai; Larry S. Zweifel; Wenqin Luo; Minghong Ma

doi:10.1038/s41467-018-03988-1

Nature Communications (Apr 2018)

Olfactory inputs modulate respiration-related rhythmic activity in the prefrontal cortex and freezing behavior

Andrew H. Moberly,
Mary Schreck,
Janardhan P. Bhattarai,
Larry S. Zweifel,
Wenqin Luo,
Minghong Ma

Affiliations

Andrew H. Moberly: Department of Neuroscience, University of Pennsylvania Perelman School of Medicine
Mary Schreck: Department of Neuroscience, University of Pennsylvania Perelman School of Medicine
Janardhan P. Bhattarai: Department of Neuroscience, University of Pennsylvania Perelman School of Medicine
Larry S. Zweifel: Department of Pharmacology and Department of Psychiatry and Behavioral Sciences, University of Washington
Wenqin Luo: Department of Neuroscience, University of Pennsylvania Perelman School of Medicine
Minghong Ma: Department of Neuroscience, University of Pennsylvania Perelman School of Medicine

DOI: https://doi.org/10.1038/s41467-018-03988-1
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 10

Abstract

Read online

Nasal airflow and olfactory bulb activity are linked to oscillations in cortical areas. This study shows olfactory input and respiration are correlated with oscillation in the prefrontal cortex during freezing behavior in mice, and attenuation of olfactory inputs can increase behavioral freezing.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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