Cellulitis with bacteremia due to multidrug-resistant Campylobacter jejuni in a case of agammaglobulinemia and bronchiectasis
Itaru Nakamura,
Takehito Kobayashi,
Masakatsu Fukuzawa,
Kohji Komori,
Tetsuo Yamaguchi
Affiliations
Itaru Nakamura
Department of Infection Prevention and Control, Tokyo Medical University Hospital, Japan
Takehito Kobayashi
Department of Infection Prevention and Control, Tokyo Medical University Hospital, Japan
Masakatsu Fukuzawa
Department of Gastroenterology and Hepatology, Tokyo Medical University Hospital, Japan
Kohji Komori
Department of Microbiology and Infectious Diseases, Faculty of Medicine, Toho University, Japan
Tetsuo Yamaguchi
Department of Microbiology and Infectious Diseases, Faculty of Medicine, Toho University, Japan; Correspondence to: Department of Microbiology and Infectious Diseases, Faculty of Medicine, Toho University, 5–21-16, Omori-nishi, Ota-ku, Tokyo 143–8540, Japan.
This case report demonstrates successful treatment outcomes without recurrence using fosfomycin for cellulitis with bacteremia caused by Campylobacter jejuni resistant to macrolides, fluoroquinolones, and tetracyclines in agammaglobulinemia and bronchiectasis. Whole-genome sequencing indicated the presence of ST137 harboring blaOXA-61 and tet(O), with mutations in the 23S rRNA and gyrA genes.