959 Safety and anti-tumor activity of TCR-engineered autologous, PRAME-directed T cells across multiple advanced solid cancers at low doses – clinical update on the ACTengine® IMA203 trial

• Harpreet Singh,
• Jason Luke,
• Mamta Kalra,
• Martin Wermke,
• Dejka Araujo,
• Ali Mohamed,
• Winfried Alsdorf,
• Apostolia-Maria Tsimberidou,
• Andrea Mayer-Mokler,
• Arun Satelli,
• Carsten Reinhardt,
• Dominik Maurer,
• George Jr Blumenschein,
• Kerstin Guenther,
• Manik Chatterjee,
• Norbert Hilf,
• Regina Mendrzyk,
• Steffen Walter,
• Stephen Eck,
• Tobias AW Holderried,
• Toni Weinschenk,
• Van Morris,
• Cedrik M Britten

Affiliations

Harpreet Singh

Genitourinary Malignancies, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA

Jason Luke

1University of Iowa, Iowa City, IA, USA

Mamta Kalra

Aff197 grid.39382.33000000012160926XBaylor College of Medicine Houston TX USA

Martin Wermke

Aff11 Early Clinical Trial UnitUniversity Cancer Center Dresden Germany

Dejka Araujo

3University of Texas MD Anderson Cancer Center, Houston, TX, USA

Ali Mohamed

Faculty of Medicine, Suez Canal University, Ismailia, Egypt

Winfried Alsdorf

4University Medical Center Eppendorf, Hamburg, Germany

Apostolia-Maria Tsimberidou

2MD Anderson Cancer Center, Houston, TX, USA

Andrea Mayer-Mokler

4Immatics Biotechnologies GmbH, Tuebingen, Germany

Arun Satelli

3Immatics US, Inc., Houston, TX, USA

Carsten Reinhardt

5Immatics N.V., Tuebingen, Germany

Dominik Maurer

4Immatics Biotechnologies GmbH, Tuebingen, Germany

George Jr Blumenschein

2MD Anderson Cancer Center, Houston, TX, USA

Kerstin Guenther

4Immatics Biotechnologies GmbH, Tuebingen, Germany

Manik Chatterjee

7University Hospital Wuerzburg, Wuerzburg, Germany

Norbert Hilf

4Immatics Biotechnologies GmbH, Tuebingen, Germany

Regina Mendrzyk

4Immatics Biotechnologies GmbH, Tuebingen, Germany

Steffen Walter

3Immatics US, Inc., Houston, TX, USA

Stephen Eck

3Immatics US, Inc., Houston, TX, USA

Tobias AW Holderried

8University Hospital Bonn, Bonn, Germany

Toni Weinschenk

5Immatics N.V., Tuebingen, Germany

Van Morris

2MD Anderson Cancer Center, Houston, TX, USA

Cedrik M Britten

5Immatics N.V., Tuebingen, Germany