Current Oncology (Sep 2024)
Internal Consistency and Floor/Ceiling Effects of the Gross Motor Function Measure for Use with Children Affected by Cancer: A Cross-Sectional Study
- Francesca Rossi,
- Monica Valle,
- Giovanni Galeoto,
- Marco Tofani,
- Paola Berchialla,
- Veronica Sciannameo,
- Daniele Bertin,
- Annalisa Calcagno,
- Roberto Casalaz,
- Margherita Cerboneschi,
- Marta Cervo,
- Annalisa Cornelli,
- Chiara Di Pede,
- Maria Esposito,
- Miriana Ferrarese,
- Paola Imazio,
- Maria Lorenzon,
- Lucia Longo,
- Andrea Martinuzzi,
- Gabriella Naretto,
- Nicoletta Orsini,
- Daniele Panzeri,
- Chiara Pellegrini,
- Michela Peranzoni,
- Fabiola Picone,
- Marco Rabusin,
- Federica Ricci,
- Claudia Zigrino,
- Giulia Zucchetti,
- Franca Fagioli
Affiliations
- Francesca Rossi
- Rehabilitation Service, Public Health and Paediatric Sciences Department, A.O.U. Città della Salute e della Scienza—Regina Margherita Children Hospital, 10126 Turin, Italy
- Monica Valle
- Department of Public Health and Pediatrics Sciences, University of Turin, 10124 Turin, Italy
- Giovanni Galeoto
- Department of Human Neurosciences, Sapienza University of Rome, 00185 Rome, Italy
- Marco Tofani
- Department of Life Sciences, Health and Allied Healthcare Professions, Università degli Studi “Link Campus University”, Via del Casale di San Pio V 44, 00165 Rome, Italy
- Paola Berchialla
- Epidemiology and Public Health, Department of Clinical and Biological Sciences, University of Turin, 10124 Turin, Italy
- Veronica Sciannameo
- Epidemiology and Public Health, Department of Clinical and Biological Sciences, University of Turin, 10124 Turin, Italy
- Daniele Bertin
- Pediatric Oncohematology, Stem Cell Transplantation and Cell Therapy Division, A.O.U. Città della Salute e della Scienza—Regina Margherita Children’s Hospital, 10126 Turin, Italy
- Annalisa Calcagno
- Physical Therapy and Rehabilitation Department, Children’s Hospital Giannina Gaslini, 16147 Genoa, Italy
- Roberto Casalaz
- Paediatric Oncohematology Unit, Institute for Maternal and Child Health—IRCCS Burlo Garofolo, 34137 Trieste, Italy
- Margherita Cerboneschi
- Rehabilitation Department, IRCCS, Meyer Children’s Hospital, 50139 Firenze, Italy
- Marta Cervo
- Rehabilitation Department, IRCCS, Meyer Children’s Hospital, 50139 Firenze, Italy
- Annalisa Cornelli
- Pediatric Oncology Department, ASST Papa Giovanni XXIII, 24127 Bergamo, Italy
- Chiara Di Pede
- Neuromotor Rehabilitation Unit, Scientific Institute, IRCCS E. Medea, 31015 Conegliano, Italy
- Maria Esposito
- Department of Public Health and Pediatrics Sciences, University of Turin, 10124 Turin, Italy
- Miriana Ferrarese
- Health Professions of Rehabilitation Sciences Master’s Degree, Clinical and Biological Sciences Department, University of Turin, 10124 Turin, Italy
- Paola Imazio
- Rehabilitation Department of Pediatric Orthopedics Unit, A.O.U. Città della Salute e della Scienza—Regina Margherita Children’s Hospital, 10126 Turin, Italy
- Maria Lorenzon
- Neuromotor Rehabilitation Unit, Scientific Institute, IRCCS E. Medea, 31015 Conegliano, Italy
- Lucia Longo
- Health Professions of Rehabilitation Sciences Master’s Degree, Clinical and Biological Sciences Department, University of Turin, 10124 Turin, Italy
- Andrea Martinuzzi
- Neuromotor Rehabilitation Unit, Scientific Institute, IRCCS E. Medea, 31015 Conegliano, Italy
- Gabriella Naretto
- Rehabilitation Department of Pediatric Orthopedics Unit, A.O.U. Città della Salute e della Scienza—Regina Margherita Children’s Hospital, 10126 Turin, Italy
- Nicoletta Orsini
- Physical Therapy and Rehabilitation Department, Children’s Hospital Giannina Gaslini, 16147 Genoa, Italy
- Daniele Panzeri
- Neuro-Oncological Rehabilitation Unit, Scientific Institute IRCCS E. Medea, 23842 Bosisio Parini, Italy
- Chiara Pellegrini
- Palliative Care, Pain Therapy and Rehabilitation Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy
- Michela Peranzoni
- Department of Physiotherapy, Hospital of Bolzano, 39100 Bolzano, Italy
- Fabiola Picone
- Rehabilitation Department, IRCCS, Meyer Children’s Hospital, 50139 Firenze, Italy
- Marco Rabusin
- Paediatric Oncohematology Unit, Institute for Maternal and Child Health—IRCCS Burlo Garofolo, 34137 Trieste, Italy
- Federica Ricci
- Department of Public Health and Pediatrics Sciences, University of Turin, 10124 Turin, Italy
- Claudia Zigrino
- Unit for Severe Disabilities in Developmental Age and Young Adults (Developmental Neurology and Neurorehabilitation), Scientific Institute IRCCS “Eugenio Medea”, 72100 Brindisi, Italy
- Giulia Zucchetti
- Pediatric Oncohematology, Stem Cell Transplantation and Cell Therapy Division, A.O.U. Città della Salute e della Scienza—Regina Margherita Children’s Hospital, 10126 Turin, Italy
- Franca Fagioli
- Pediatric Oncohematology, Stem Cell Transplantation and Cell Therapy Division, A.O.U. Città della Salute e della Scienza—Regina Margherita Children’s Hospital, 10126 Turin, Italy
- DOI
- https://doi.org/10.3390/curroncol31090390
- Journal volume & issue
-
Vol. 31,
no. 9
pp. 5291 – 5306
Abstract
Children/adolescents with cancer can develop adverse effects impacting gross motor function. There is a lack of gross motor function assessment tools that have been validated for this population. The aim of this multicenter cross-sectional study was to preliminary validate the 88-item Gross Motor Function Measure (GMFM-88) for use in children/adolescents with cancer, exploring internal consistency and floor/ceiling effect. Inclusion criteria regarded children/adolescents diagnosed with cancer on treatment or <1 year off therapy. The internal consistency was assessed using Cronbach’s α, and the floor–ceiling effects were calculated through percentage. This study involved 217 participants with heterogeneous neoplasm conditions. Internal consistency was good, with a Cronbach’s α of 0.989. Floor–ceiling effect analysis reveals that several items obtained a dichotomous scoring distribution in each of the five sub-scales of the GMFM-88. This can be explained by the heterogeneous clinical characteristics of the target population. The preliminary validation of GMFM-88 in a group of children/adolescents affected by cancer suggests that some items are not able to discriminate between different gross motor function levels, and therefore it does not represent an informative tool to measure gross motor function in children with cancer. Future research is needed to define which ones could be more useful for clinical practice.
Keywords
