International Journal of Molecular Sciences (Jul 2007)

Dinuclear Zinc (II) Complexes of Macrocyclic Polyamine Ligands Containing an Imidazolium Bridge: Synthesis, Characterization, and Their Interaction with Plasmid DNA

  • Xiao-Qi Yu,
  • Jiang Wu,
  • Hong-Hui Lin,
  • Ning Jiang,
  • Kun Li,
  • Qiang-Lin Li,
  • Li-Hong Zhou,
  • Ji Zhang,
  • Qing-Dong Huang,
  • Jun Huang

DOI
https://doi.org/10.3390/i8070606
Journal volume & issue
Vol. 8, no. 7
pp. 606 – 617

Abstract

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Two novel macrocyclic polyamine ligands and their dinuclear zinc (II)complexes were synthesized and characterized. Their interaction with plasmid DNA wasstudied by gel electrophoresis and fluorescence quenching experiment. The result showedthat these complexes could bind DNA efficiently under physiological conditions.

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