Medical Journal of The Islamic Republic of Iran (Nov 2012)

A rare ovarian tumor, leydig stromal cell tumor, presenting with virilization: a case report

  • Soheila Aminimoghaddam,
  • Atefeh-Sadat Ebrahimi,
  • Forough Hashemi

Journal volume & issue
Vol. 26, no. 4
pp. 185 – 188

Abstract

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 Abstract Leydig stromal cell tumor is a rare ovarian tumor that belongs to the group of sex-cord stromal tumors. They produce testosterone leading to hyperandrogenism. We present a 41yr old woman with symptoms of virilization and a mass of right adenex via ultra Sonography, and a rise of total and free serum testosterone. An ovarian source of androgen was suspected and a surgery performed. A diagnosis of leydig-stromal cell tumor was confirmed. Our report is a reminder that although idiopathic hirsutism and other benign androgen excess disorder like Polycystic Ovarian Syndrome (PCOs) are common, ovarian mass should be considered in differential diagnosis. 

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