Daily Physical Activity Assessed by a Triaxial Accelerometer Is Beneficially Associated with Waist Circumference, Serum Triglycerides, and Insulin Resistance in Japanese Patients with Prediabetes or Untreated Early Type 2 Diabetes

Journal of Diabetes Research. 2015;2015 DOI 10.1155/2015/526201

 

Journal Homepage

Journal Title: Journal of Diabetes Research

ISSN: 2314-6745 (Print); 2314-6753 (Online)

Publisher: Hindawi Limited

LCC Subject Category: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology

Country of publisher: United Kingdom

Language of fulltext: English

Full-text formats available: PDF, HTML, ePUB, XML

 

AUTHORS


Hidetaka Hamasaki (Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba 272-8516, Japan)

Mitsuhiko Noda (Department of Diabetes Research, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo 162-8655, Japan)

Sumie Moriyama (Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba 272-8516, Japan)

Reo Yoshikawa (Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba 272-8516, Japan)

Hisayuki Katsuyama (Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba 272-8516, Japan)

Akahito Sako (Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba 272-8516, Japan)

Shuichi Mishima (Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba 272-8516, Japan)

Masafumi Kakei (General Internal Medicine, Community Healthcare Studies, Jichi Medical University Graduate School, Tochigi 329-0498, Japan)

Osamu Ezaki (Department of Human Health and Design, Faculty of Human Life and Environmental Sciences, Showa Women’s University, Tokyo 154-8533, Japan)

Hidekatsu Yanai (Department of Internal Medicine, National Center for Global Health and Medicine Kohnodai Hospital, Chiba 272-8516, Japan)

EDITORIAL INFORMATION

Blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 14 weeks

 

Abstract | Full Text

Aim. To investigate the association between daily physical activity and metabolic risk factors in Japanese adults with prediabetes or untreated early type 2 diabetes (T2D). Methods. Daily physical activity level was measured using a triaxial accelerometer. We assessed correlations between physical activity level and waist circumference, blood pressure, fasting levels of plasma glucose, serum triglycerides, and insulin and homeostasis model assessment-insulin resistance (HOMA-IR). Results. A total of 80 patients were studied. After adjustment for age and body mass index, in all subjects, physical activity level was negatively associated with waist circumference (β=-0.124, P=0.018) and fasting serum triglycerides (β=-0.239, P=0.035), insulin (β=-0.224, P=0.022). In men, physical activity level was negatively associated with systolic blood pressure (β=-0.351, P=0.044), fasting plasma glucose (β=-0.369, P=0.025) and insulin (β=-0.362, P=0.012), and HOMA-IR (β=-0.371, P=0.011). No significant associations were found between physical activity level and metabolic risk factors in women. Conclusion. Objectively measured daily physical activity is beneficially associated with waist circumference, serum triglycerides, and insulin resistance in individuals with prediabetes or untreated early T2D. (This trial is registered with UMIN000015774.)