Life (May 2024)

Consequences of Maternal Vitamin D Deficiency on Newborn Health

  • Ramona Elena Dragomir,
  • Daniela Oana Toader,
  • Daniela Elena Gheoca Mutu,
  • Iulian Alexandru Dogaru,
  • Laura Răducu,
  • Laurențiu Cezar Tomescu,
  • Lavinia Cristina Moleriu,
  • Anca Bordianu,
  • Ion Petre,
  • Ruxandra Stănculescu

DOI
https://doi.org/10.3390/life14060714
Journal volume & issue
Vol. 14, no. 6
p. 714

Abstract

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Background and Objectives: Maternal–fetal gestational pathology is one of the biggest challenges in the field of health at this moment. The current study is designed to determine the effects of vitamin D on pregnancy, starting with the idea that impairment of vitamin D status is thought to be correlated with impairment of the newborn’s health. Materials and Methods: In this retrospective study, we tried to establish the link between vitamin D deficiency and maternal characteristics and also how it impacted the clinical status of the newborn. We analyzed a group of 260 patients: 130 pregnant women and 130 newborns, in whom vitamin D status was detected using the serum levels of 25-hydroxyvitamin D (25-(OH)D). Results: The results showed that vitamin D deficiency has a high incidence among pregnant women, as was presented in many important international studies. Our study also showed a positive, direct correlation between the mother’s and newborn’s vitamin D status. Conclusions: Taking into consideration that vitamin D deficiency has been correlated with many complications, both in maternal and newborn health, a serum level determination of 25-(OH)D is necessary in the first trimester of pregnancy, and after that, adequate supplementation is necessary in order to prevent any negative effects.

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