Consequences of Maternal Vitamin D Deficiency on Newborn Health
Ramona Elena Dragomir,
Daniela Oana Toader,
Daniela Elena Gheoca Mutu,
Iulian Alexandru Dogaru,
Laura Răducu,
Laurențiu Cezar Tomescu,
Lavinia Cristina Moleriu,
Anca Bordianu,
Ion Petre,
Ruxandra Stănculescu
Affiliations
Ramona Elena Dragomir
Doctoral School, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
Daniela Oana Toader
Department of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
Daniela Elena Gheoca Mutu
Discipline of Anatomy, Department 2—Morphological Sciences, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
Iulian Alexandru Dogaru
Doctoral School, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
Laura Răducu
Discipline of Plastic Surgery, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
Laurențiu Cezar Tomescu
Department of Obstetrics and Gynecology, “Ovidius” University of Constanța, 900527 Constanța, Romania
Lavinia Cristina Moleriu
Discipline of Medical Informatics and Biostatistics, Department 3—Functional Sciences, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timisoara, Romania
Anca Bordianu
Discipline of Plastic Surgery, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
Ion Petre
Discipline of Medical Informatics and Biostatistics, Department 3—Functional Sciences, “Victor Babeș” University of Medicine and Pharmacy, 300041 Timisoara, Romania
Ruxandra Stănculescu
Doctoral School, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
Background and Objectives: Maternal–fetal gestational pathology is one of the biggest challenges in the field of health at this moment. The current study is designed to determine the effects of vitamin D on pregnancy, starting with the idea that impairment of vitamin D status is thought to be correlated with impairment of the newborn’s health. Materials and Methods: In this retrospective study, we tried to establish the link between vitamin D deficiency and maternal characteristics and also how it impacted the clinical status of the newborn. We analyzed a group of 260 patients: 130 pregnant women and 130 newborns, in whom vitamin D status was detected using the serum levels of 25-hydroxyvitamin D (25-(OH)D). Results: The results showed that vitamin D deficiency has a high incidence among pregnant women, as was presented in many important international studies. Our study also showed a positive, direct correlation between the mother’s and newborn’s vitamin D status. Conclusions: Taking into consideration that vitamin D deficiency has been correlated with many complications, both in maternal and newborn health, a serum level determination of 25-(OH)D is necessary in the first trimester of pregnancy, and after that, adequate supplementation is necessary in order to prevent any negative effects.
