Journal of Indian Society of Pedodontics and Preventive Dentistry (Jan 2011)

The relationship between salivary IgA levels and dental caries in children

  • E Ranadheer,
  • Ullal Anand Nayak,
  • N Venugopal Reddy,
  • V Arun Prasad Rao

DOI
https://doi.org/10.4103/0970-4388.84681
Journal volume & issue
Vol. 29, no. 2
pp. 106 – 112

Abstract

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Purpose: The aim of the study was to find the relationship between salivary IgA (s-IgA) levels and dental caries in children. Materials and Methods: A total of 40 children in the age group of 8 to 12 years were selected and divided into two groups. Group I with DMFT score 0 and Group II with DMFT score ≥3. The whole unstimulated s-IgA levels were estimated using ELISA method. Results: Whole s-IgA levels were significantly higher in group II with DMFT score ≥3 as compared with group I with DMFT score 0. Conclusions: There was an increase in s-IgA levels in caries-active mouth to give protection mechanism against dental caries and the Streptococcus mutans which are active in caries-active mouth. The s-IgA antibodies can play an important role in control of dental caries.

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