Clinical Dermatology Review (Jan 2019)

Hydroa vacciniforme-like lymphoma

  • Zhang Fang,
  • Yang Huizhi,
  • Shi Jianqiang,
  • Lin Jiaxi,
  • Cai Yanxia,
  • Chen Rongyi

DOI
https://doi.org/10.4103/CDR.CDR_4_19
Journal volume & issue
Vol. 3, no. 2
pp. 139 – 141

Abstract

Read online

Hydroa vacciniforme-like lymphoma is a rare cutaneous T-cell lymphoma occurring in children associated with Epstein–Barr virus (EBV) infection. We reported a 15-year-old Chinese boy who presented with a 3-month history of recurrent special clinical manifestations including vesicles, erythematous papules, ulcer, crusting, and smallpox-like scar on his head, face, neck, limbs, and ankles. EBV-DNA level was positive. Immunohistochemistry showed CD2(+++), CD3(+++), CD4(+), CD5(++), CD7(+), CD8(±), CD56(+), ki67 (30%+), Gr-B(+++). The patient showed a significant improvement in clinical symptoms after being treated with interferon alpha and prednisone.

Keywords