Nature Communications (Jan 2023)

Distributed context-dependent choice information in mouse posterior cortex

  • Javier G. Orlandi,
  • Mohammad Abdolrahmani,
  • Ryo Aoki,
  • Dmitry R. Lyamzin,
  • Andrea Benucci

DOI
https://doi.org/10.1038/s41467-023-35824-6
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 16

Abstract

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In the posterior cortex, which is involved in decision making, the strength and area specificity of choice signals are highly variable. Here the authors show that the representation of choice in the posterior area of the mouse brain is orthogonal to that of sensory and movement-related signals, with modulations determined by task features and cognitive demands.