Prepectoral versus subpectoral implant-based breast reconstruction after skin-sparing mastectomy or nipple-sparing mastectomy (OPBC-02/ PREPEC): a pragmatic, multicentre, randomised, superiority trial

• Andrea L Pusic,
• Matthias Schwenkglenks,
• Karin Ribi,
• Lars G Hemkens,
• Jane Shaw,
• Christian Kurzeder,
• Shelley Potter,
• Joerg Heil,
• Heiner C Bucher,
• Frank Zimmermann,
• Sherko Kuemmel,
• Elisabeth A Kappos,
• Alexandra Schulz,
• Meredith M Regan,
• Giusi Moffa,
• Yves Harder,
• Mathias K Fehr,
• Thomas Holzbach,
• Jian Farhadi,
• Colin Simonson,
• Michael Knauer,
• Ralph Verstappen,
• Daniel Zwahlen,
• Rosine Mucklow,
• Vesna Bjelic-Radisic,
• Amelia Chiorescu,
• Yoon S Chun,
• Subrina Farah,
• Chen Xiaosong,
• Linda Nigard,
• Roland Reitsamer,
• Maik Hauschild,
• Ilario Fulco,
• Christoph Tausch,
• Thomas Fischer,
• Dimitri Sarlos,
• Mihai A Constantinescu,
• Judith E Lupatsch,
• Florian Fitzal,
• Zoltan Matrai,
• Jana de Boniface,
• Martin Haug,
• Walter P Weber

Affiliations

Andrea L Pusic

Department of Surgery, Patient Reported Outcome, Value, and Experience (PROVE) Center, Harvard Medical School, Brigham and Women’s Hospital, Boston, Massachusetts, USA

Matthias Schwenkglenks

professor

Karin Ribi

2 IUFRS Institut de formation et de recherche en soins, Université de Lausanne Faculté de biologie et médecine, Lausanne, Switzerland

Lars G Hemkens

senior scientist

Jane Shaw

9 Department of Pain Medicine, The James Cook University Hospital, Middlesbrough, UK

Christian Kurzeder

7 SAKK & University Hospital of Basel, Basel, Switzerland

Shelley Potter

Bristol Centre for Surgical Research, Population Health Sciences, Bristol Medical School, Bristol, UK

Joerg Heil

9 University Hospital Heidelberg, Heidelberg, Germany

Heiner C Bucher

professor

Frank Zimmermann

Department of Radiation Oncology, University Hospital Basel, Basel, BS, Switzerland

Sherko Kuemmel

West German Study Group, Moenchengladbach, Germany

Elisabeth A Kappos

1 Breast Center, University Hospital Basel, University of Basel, Basel, Switzerland

Alexandra Schulz

3 University of Basel, Basel, Switzerland

Meredith M Regan

5 IBCSG Statistical Center, Division of Biostatistics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA

Giusi Moffa

6 Department of Mathematics and Computer Science, University of Basel, Basel, Switzerland

Yves Harder

7 Department of Plastic, Reconstructive and Aesthetic Surgery, Ospedale Regionale di Lugano and Centro di Senologia della Svizzera Italiana, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland

Mathias K Fehr

12 Department of Gynecology and Obstetrics, Cantonal Hospital Frauenfeld, Frauenfeld, Switzerland

Thomas Holzbach

16 Department of Hand and Plastic Surgery, Spital Thurgau AG, Frauenfeld, Thurgau, Switzerland

Jian Farhadi

3 University of Basel, Basel, Switzerland

Colin Simonson

20 Brustzentrum Spital Sitten, Sitten, Switzerland

Michael Knauer

21 Breast Center Eastern Switzerland, St. Gallen, Switzerland

Ralph Verstappen

22 Breast Center St. Gallen, St. Gallen Cantonal Hospital, St. Gallen, Switzerland

Daniel Zwahlen

24 Department of Radiation Oncology, Kantonsspital Winterthur, Winterthur, Switzerland

Rosine Mucklow

28 Independent patient expert, Buxtorf Quality Services, Basel, Switzerland

Vesna Bjelic-Radisic

30 Breast Unit, University Hospital Helios Wuppertal, University Witten Herdecke, Wuppertal, Germany

Amelia Chiorescu

31 Department of Breast, Endocrine tumours and Sarcoma, Theme Cancer, Karolinska University Hospital, Stockholm, Sweden

Yoon S Chun

11 Division of Plastic and Reconstructive Surgery, Department of Surgery, Harvard Medical School, Brigham and Women’s Hospital, Boston, Massachusetts, USA

Subrina Farah

5 IBCSG Statistical Center, Division of Biostatistics, Dana-Farber Cancer Institute, Boston, Massachusetts, USA

Chen Xiaosong

33 Comprehensive Breast Health Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Linda Nigard

34 Södersjukhuset, Bröstsektionen, Kirurgkliniken, Stockholm, Sweden

Roland Reitsamer

37 Breast Center Salzburg, University Clinic Salzburg, Paracelsus Medical University Salzburg, Salzburg, Austria

Maik Hauschild

38 Department of Gynecology and Obstetrics, Gesundheitszentrum Fricktal, Rheinfelden, Switzerland

Ilario Fulco

1 Breast Center, University Hospital Basel, University of Basel, Basel, Switzerland

Christoph Tausch

18 Breast Center Zurich, Zurich, Switzerland

Thomas Fischer

40 Lindenhofgruppe, Centerclinic, Brustzentrum Bern, Bern, Switzerland

Dimitri Sarlos

41 Department of Obstetrics and Gynecology, Kantonsspital Aarau AG, Aarau, Switzerland

Mihai A Constantinescu

42 Department of Plastic and Hand Surgery, Inselspital University Hospital, Bern, Switzerland

Judith E Lupatsch

26 Institute of Pharmaceutical Medicine (ECPM), University of Basel, Basel, Switzerland

Florian Fitzal

44 Breast Health Center and Department of Surgery, Medical University, Vienna, Austria

Zoltan Matrai

46 National Institute of Oncology, Department of Breast and Sarcoma Surgery, Budapest, Hungary

Jana de Boniface

32 Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

Martin Haug

1 Breast Center, University Hospital Basel, University of Basel, Basel, Switzerland

Walter P Weber

1 Breast Center, University Hospital Basel, University of Basel, Basel, Switzerland