Nature Communications (Aug 2020)
Single-neuron representation of learned complex sounds in the auditory cortex
- Meng Wang,
- Xiang Liao,
- Ruijie Li,
- Shanshan Liang,
- Ran Ding,
- Jingcheng Li,
- Jianxiong Zhang,
- Wenjing He,
- Ke Liu,
- Junxia Pan,
- Zhikai Zhao,
- Tong Li,
- Kuan Zhang,
- Xingyi Li,
- Jing Lyu,
- Zhenqiao Zhou,
- Zsuzsanna Varga,
- Yuanyuan Mi,
- Yi Zhou,
- Junan Yan,
- Shaoqun Zeng,
- Jian K. Liu,
- Arthur Konnerth,
- Israel Nelken,
- Hongbo Jia,
- Xiaowei Chen
Affiliations
- Meng Wang
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Xiang Liao
- Center for Neurointelligence, School of Medicine, Chongqing University
- Ruijie Li
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Shanshan Liang
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Ran Ding
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Jingcheng Li
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Jianxiong Zhang
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Wenjing He
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Ke Liu
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Junxia Pan
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Zhikai Zhao
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Tong Li
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Kuan Zhang
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Xingyi Li
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- Jing Lyu
- Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences
- Zhenqiao Zhou
- Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences
- Zsuzsanna Varga
- Institute of Neuroscience and the SyNergy Cluster, Technical University Munich
- Yuanyuan Mi
- Center for Neurointelligence, School of Medicine, Chongqing University
- Yi Zhou
- Advanced Institute for Brain and Intelligence, Guangxi University
- Junan Yan
- Advanced Institute for Brain and Intelligence, Guangxi University
- Shaoqun Zeng
- Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics-Huazhong University of Science and Technology, Department of Biomedical Engineering, Key Laboratory for Biomedical Photonics of Ministry of Education, Huazhong University of Science and Technology
- Jian K. Liu
- Centre for Systems Neuroscience, Department of Neuroscience, Psychology and Behaviour, University of Leicester
- Arthur Konnerth
- Institute of Neuroscience and the SyNergy Cluster, Technical University Munich
- Israel Nelken
- The Edmond and Lily Safra Center for Brain Sciences, and the Department of Neurobiology, Silberman Institute of Life Sciences, Hebrew University
- Hongbo Jia
- Brain Research Instrument Innovation Center, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences
- Xiaowei Chen
- Brain Research Center and State Key Laboratory of Trauma, Burns, and Combined Injury, Third Military Medical University
- DOI
- https://doi.org/10.1038/s41467-020-18142-z
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 14
Abstract
Using a combination of two-photon imaging and single-cell electrophysiology, the authors discover that associative learning induces the emergence of a unique subset of neurons in the auditory cortex, exhibiting high-rate bursting responses to the learned complex sounds but not to any of the constituents.
