Nutrients (Oct 2021)

Nutraceuticals for Peripheral Vestibular Pathology: Properties, Usefulness, Future Perspectives and Medico-Legal Aspects

  • Giuseppe Chiarella,
  • Gianmarco Marcianò,
  • Pasquale Viola,
  • Caterina Palleria,
  • Davide Pisani,
  • Vincenzo Rania,
  • Alessandro Casarella,
  • Alessia Astorina,
  • Alfonso Scarpa,
  • Massimiliano Esposito,
  • Monica Salerno,
  • Nunzio Di Nunno,
  • Matteo Bolcato,
  • Amalia Piscopo,
  • Erika Cione,
  • Giovambattista De Sarro,
  • Giulio Di Mizio,
  • Luca Gallelli

DOI
https://doi.org/10.3390/nu13103646
Journal volume & issue
Vol. 13, no. 10
p. 3646

Abstract

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Vestibular disorders may generate complex signs and symptoms, which may alter patients’ balance and the quality of life. Dizziness and vertigo can strongly affect daily activities and relations. Despite the presence of conventional drugs, maneuvers, and surgery, another interesting therapeutic opportunity is offered by nutraceuticals. These molecules are often used in the treatment of dizziness and vertigo, but the rationale of their application is not always solidly demonstrated by the scientific evidence. Several substances have shown a variable level of efficacy/usefulness in this field, but there is lack of important evidence for most of them. From a medico-legal point of view, specific information must be provided to the patient regarding the efficacy and possibilities that the use of these preparations can allow. Administering the right nutraceutical to the proper patient is a fundamental clinical skill. Integrating conventional drug treatment with nutraceutical administration seems to be easy, but it may be difficult considering the (in part unexplored) pharmacodynamics and pharmacokinetics of nutraceuticals. The aim of the scientific community should be to elevate nutraceuticals to the same law and technical dignity of conventional drugs.

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