Physiologically Based Pharmacokinetic Modeling in Pregnancy, during Lactation and in Neonates: Achievements, Challenges and Future Directions
Karel Allegaert,
Sara K. Quinney,
André Dallmann
Affiliations
Karel Allegaert
Clinical Pharmacology and Pharmacotherapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, 3000 Leuven, Belgium
Sara K. Quinney
Department of OB/GYN, Maternal and Pediatric Precision in Therapeutics (MPRINT) Hub, Indiana University School of Medicine, Indianapolis, IN 46202, USA
André Dallmann
Bayer HealthCare SAS, Loos, France, on Behalf of Bayer AG, Pharmacometrics/Modeling and Simulation, Systems Pharmacology & Medicine–PBPK, 51368 Leverkusen, Germany