Metabolic effects of nettle extract in diabetes mellitus

Abstract

The blood level of glucose, glycosylated hemoglobin, triglycerides, total cholesterol, summary content of very low density and low density lipoproteins, high density lipoproteins glycosylation's degree had been decreased with the nettle (Urtica dioica) extract in experimental diabetes mellitus type II in rats that was being caused with streptozotocine intraperitoneal injection and high-fat diet. The effect did not depend on food regimen during the therapy. The cholesterol atherogenic index has been decreased and the sensitivity to insulin has been recovered with the nettle extract when high-fat diet only. The level of blood glucose and glycosylated hemoglobin has been decreased with metformin when usual food regimen during the therapy. The lipid content and cholesterol atherogenic index has been normalized with metformin when both variant of diet.

Keywords

• модель сахарного диабета типа 2
• экстракт крапивы
• метформин
• гипергликемия
• дислипидемия