The modern view on diabetic cardiomyopathy

Abstract

Diabetes mellitus (DM) is a serious medico-social problem, due to high risk of its complications and, as a result, high prevalence of disability in DM patients. DM substantially increases the risk of heart failure (HF), mostly because of diabetic cardiomyopathy (DCMP). The development of the latter is influenced by many factors, sharing the main pathophysiological mechanism – insulin resistance. The paper discusses in detail the mechanisms of DCMP development and the principal relevant factors.

Keywords

• diabetic cardiomyopathy
• diabetes mellitus
• microangiopathy
• macroangiopathy
• endothelial dysfunction
• left ventricular hypertrophy
• arterial hypertension