Molecules (Dec 2012)

Cross-Coupling Reaction with Lithium Methyltriolborate

  • Norio Miyaura,
  • Hajime Ito,
  • Yasunori Yamamoto,
  • Kazuya Ikizakura

DOI
https://doi.org/10.3390/molecules18010430
Journal volume & issue
Vol. 18, no. 1
pp. 430 – 439

Abstract

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We newly developed lithium methyltriolborate as an air-stable white solid that is convenient to handle. The good performance of this triolborate for metal-catalyzed bond-forming reactions was demonstrated in palladium-catalyzed cross-coupling reactions with haloarenes. Cross-coupling reaction of [MeB(OCH2)3CCH3]Li with aryl halides occurred in the presence of Pd(OAc)2/RuPhos complex in refluxing MeOH/H2O and the absence of bases.

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