Frontiers in Immunology (Feb 2024)
Neutrophil extracellular traps in bacterial infections and evasion strategies
- Ahmed Adel Baz,
- Ahmed Adel Baz,
- Ahmed Adel Baz,
- Ahmed Adel Baz,
- Ahmed Adel Baz,
- Huafang Hao,
- Huafang Hao,
- Huafang Hao,
- Huafang Hao,
- Shimei Lan,
- Shimei Lan,
- Shimei Lan,
- Shimei Lan,
- Zhangcheng Li,
- Zhangcheng Li,
- Zhangcheng Li,
- Zhangcheng Li,
- Shuang Liu,
- Shuang Liu,
- Shuang Liu,
- Shuang Liu,
- Shengli Chen,
- Shengli Chen,
- Shengli Chen,
- Shengli Chen,
- Yuefeng Chu,
- Yuefeng Chu,
- Yuefeng Chu,
- Yuefeng Chu
Affiliations
- Ahmed Adel Baz
- State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China
- Ahmed Adel Baz
- Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China
- Ahmed Adel Baz
- Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Ahmed Adel Baz
- Key Laboratory of Veterinary Etiological Biology, Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Ahmed Adel Baz
- Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Assiut, Egypt
- Huafang Hao
- State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China
- Huafang Hao
- Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China
- Huafang Hao
- Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Huafang Hao
- Key Laboratory of Veterinary Etiological Biology, Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Shimei Lan
- State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China
- Shimei Lan
- Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China
- Shimei Lan
- Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Shimei Lan
- Key Laboratory of Veterinary Etiological Biology, Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Zhangcheng Li
- State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China
- Zhangcheng Li
- Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China
- Zhangcheng Li
- Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Zhangcheng Li
- Key Laboratory of Veterinary Etiological Biology, Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Shuang Liu
- State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China
- Shuang Liu
- Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China
- Shuang Liu
- Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Shuang Liu
- Key Laboratory of Veterinary Etiological Biology, Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Shengli Chen
- State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China
- Shengli Chen
- Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China
- Shengli Chen
- Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Shengli Chen
- Key Laboratory of Veterinary Etiological Biology, Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Yuefeng Chu
- State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China
- Yuefeng Chu
- Gansu Province Research Center for Basic Disciplines of Pathogen Biology, Lanzhou, China
- Yuefeng Chu
- Key Laboratory of Ruminant Disease Prevention and Control (West), Ministry of Agricultural and Rural Affairs, Lanzhou, China
- Yuefeng Chu
- Key Laboratory of Veterinary Etiological Biology, Ministry of Agricultural and Rural Affairs, Lanzhou, China
- DOI
- https://doi.org/10.3389/fimmu.2024.1357967
- Journal volume & issue
-
Vol. 15
Abstract
Neutrophils are innate immune cells that have a vital role in host defense systems. Neutrophil extracellular traps (NETs) are one of neutrophils’ defense mechanisms against pathogens. NETs comprise an ejected lattice of chromatin associated with histones, granular proteins, and cytosolic proteins. They are thought to be an efficient strategy to capture and/or kill bacteria and received intensive research interest in the recent years. However, soon after NETs were identified, it was observed that certain bacteria were able to evade NET entrapment through many different mechanisms. Here, we outline the recent progress of NETs in bacterial infections and the strategies employed by bacteria to evade or withstand NETs. Identifying the molecules and mechanisms that modulate NET release will improve our understanding of the functions of NETs in infections and provide new avenues for the prevention and treatment of bacterial diseases.
Keywords
