Design and optimization of immediate release tablet of salbutamol sulphate by direct compression technique

Abstract

This study is about a tablet, which disintegrates or dissolves quickly when placed in the oral cavity. Studies on formulation development of Salbutamol Sulphate Immediate Release Tablet, suitable for manufacturing by direct compression have been carried out. Trial formulations using various excipients were developed and evaluated for various qualities like hardness, friability, disintegration time, content uniformity and dissolution. Study concluded that Immediate Release Tablet of Salbutamol Sulphate can be prepared successfully with added patient benefit and increased consumer satisfaction.

Keywords

• salbutamol sulphate
• immediate release drug delivery system
• immediate release tablet
• super disintegrant