The modern paradigm of pathophysiology, prevention and treatment of heart failure in type 2 diabetes mellitus

Abstract

Prevention and choice of therapeutic strategies in patient,s with type 2 diabetes (T2D) and heart failure (HF) is an urgent problem. This review presents a modern concept for HF development from early stages of T2D. Glucose-lowering and cardiac medications for the prevention and treatment of HF depending on its phenotypes were considered.

Keywords

• diabetes
• heart failure
• subclinical myocardial dysfunction
• diabetic cardiomyopathy
• diabetic nephropathy
• preserved ejection fraction
• pathophysiology
• sglt2 inhibitors