(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine

Abstract

New (2,3-dihydro-1H-indol-5-ylmethyl)amine was synthesized from 2-((1-acetylindolin-5-yl)methyl)isoindoline-1,3-dione by simultaneous deprotection of phthalimide and acetyl groups. The structure of the newly synthesized compounds was established by elemental analysis, high resolution mass-spectrometry, 1H, 13C NMR and IR spectroscopy and mass-spectrometry. The resulting compound is a convenient intermediate for various disubstituted 1-(indolin-5-yl)methanamines, which may be of interest as substances with useful pharmacological properties.

Keywords

• 2,3-dihydroindoles (indolines)
• (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine
• deprotection
• biological activity