Use of cone-beam computed tomography for evaluation of surgical specimen of medication-related osteonecrosis of the jaw

Abstract

Cone-beam computed tomography (CBCT) provides accurate anatomical details in three-dimensional and multiplanar reformation images for diagnosis and treatment planning. We examined one surgical specimen of medication-related osteonecrosis of the jaw (MRONJ) by CBCT. CBCT images of the surgical specimen of MRONJ showed osteolytic changes in the jaws, sclerotic lesion, and sequestrum separation. Furthermore, high-resolution mode (tube voltage, 90.0 kV; tube current, 4.00 mA; rotation time,16.8 s; field of view, 56 mm × 56 mm; thickness, 0.099 mm) was sharper than standard mode (tube voltage, 90.0 kV; tube current, 4.00 mA; rotation time, 16.8 s; field of view, 81 mm × 81 mm; thickness, 0.144 mm) and high-density mode (tube voltage, 90.0 kV; tube current, 4.00 mA; rotation time, 33.5 s; field of view, 81 mm × 81 mm; thickness, 0.144 mm). We showed that CBCT, especially the high-resolution mode, is useful for the evaluation of surgical specimen of the jaw, such as MRONJ. This report can be used for reference in future studies and in clinical settings.

Keywords

• Cone-beam computed tomography
• image quality
• medication-related osteonecrosis of the jaw
• osteonecrosis