Nature Communications (May 2016)

A method to rapidly create protein aggregates in living cells

  • Yusuke Miyazaki,
  • Kota Mizumoto,
  • Gautam Dey,
  • Takamasa Kudo,
  • John Perrino,
  • Ling-chun Chen,
  • Tobias Meyer,
  • Thomas J. Wandless

DOI
https://doi.org/10.1038/ncomms11689
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 7

Abstract

Read online

Protein aggregates are associated with a wide variety of diseases. Here, in order to address how protein aggregation affects cellular homoeostasis, the authors describe a method to rapidly create protein aggregates in living cells and organisms with precise spatial and temporal control.