Leptin levels in children with malnutrition

Resky Devi Akib; Aminuddin Aminuddin; Firdaus Hamid; Prihantono Prihantono; Burhanuddin Bahar; Veni Hadju

doi:10.1016/j.gaceta.2021.10.033

Gaceta Sanitaria (Jan 2021)

Leptin levels in children with malnutrition

Resky Devi Akib,
Aminuddin Aminuddin,
Firdaus Hamid,
Prihantono Prihantono,
Burhanuddin Bahar,
Veni Hadju

Affiliations

Resky Devi Akib: Department of Midwifery, Graduate School, Hasanuddin University, Indonesia; Corresponding author.
Aminuddin Aminuddin: Departement of Nutrition, Faculty of Medicine, Hasanuddin University, Indonesia
Firdaus Hamid: Department of Microbiology, Faculty of Medicine, Hasanuddin University, Indonesia
Prihantono Prihantono: Department of Surgery, Faculty of Medicine, Hasanuddin University, Indonesia
Burhanuddin Bahar: Department of Nutrition, Faculty of Public Health, Hasanuddin University, Indonesia
Veni Hadju: Department of Midwifery, Graduate School, Hasanuddin University, Indonesia; Departement of Nutrition, Faculty of Medicine, Hasanuddin University, Indonesia; Department of Microbiology, Faculty of Medicine, Hasanuddin University, Indonesia; Department of Surgery, Faculty of Medicine, Hasanuddin University, Indonesia; Department of Nutrition, Faculty of Public Health, Hasanuddin University, Indonesia

DOI: https://doi.org/10.1016/j.gaceta.2021.10.033
Journal volume & issue: Vol. 35
pp. S278 – S280

Abstract

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Objective: This study aimed at comparing serum levels of leptin in children with malnutrition and good nutritional status. Method: This cross-sectional study included 41 participants consisting of 31 malnutrition, 10 well-nourished children aged between 36 and 60 months. Demographic data of participants were obtained utilizing a questionnaire. Nutritional status was determined by calculating the Z-score of body weight for age, height for age, and body weight for height indices using the WHO classification. Leptin levels were determined by ELISA (Enzyme-Linked Immunosorbent Assay) method. Results: Median serum leptin level for malnutrition children were found to be lower, i.e., 9.23 (6.02–197.2) ng/mL compared to well-nourished children 30.95 (6.02–89.36) ng/mL. Conclusion: Serum leptin levels can be used as indicators to assess nutritional status.

Published in Gaceta Sanitaria

ISSN: 0213-9111 (Print); 1578-1283 (Online)
Publisher: Elsevier
Country of publisher: Spain
LCC subjects: Medicine: Public aspects of medicine
Website: https://www.gacetasanitaria.org/es/

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Abstract

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