New Chalcogen-Functionalized Naphthoquinones: Design, Synthesis, and Evaluation, In Vitro and In Silico, against Squamous Cell Carcinoma

• Luana da Silva Gomes,
• Érica de Oliveira Costa,
• Thuany G. Duarte,
• Thiago S. Charret,
• Raquel C. Castiglione,
• Rafael L. Simões,
• Vinicius D. B. Pascoal,
• Thiago H. Döring,
• Fernando de C. da Silva,
• Vitor F. Ferreira,
• Aldo S. de Oliveira,
• Aislan C. R. F. Pascoal,
• André L. S. Cruz,
• Vanessa Nascimento

Affiliations

Luana da Silva Gomes

SupraSelen Laboratory, Department of Organic Chemistry, Institute of Chemistry, Federal University Fluminense, Niterói-RJ, Brazil

Érica de Oliveira Costa

SupraSelen Laboratory, Department of Organic Chemistry, Institute of Chemistry, Federal University Fluminense, Niterói-RJ, Brazil

Thuany G. Duarte

SupraSelen Laboratory, Department of Organic Chemistry, Institute of Chemistry, Federal University Fluminense, Niterói-RJ, Brazil

Thiago S. Charret

Research Laboratory of Natural Products and Bioactive Molecules, Nova Friburgo Health Institute, Fluminense Federal University (ISNF-UFF), Nova Friburgo-RJ, Brazil

Raquel C. Castiglione

Laboratory for Clinical and Experimental Research on Vascular Biology, Biomedical Center, State University of Rio de Janeiro, Rio de Janeiro-RJ, Brazil

Rafael L. Simões

Laboratory of Molecular and Cellular Pharmacology, Roberto Alcântara Gomes Biology Institute, State University of Rio de Janeiro, Rio de Janeiro, Brazil

Vinicius D. B. Pascoal

Research Laboratory of Natural Products and Bioactive Molecules, Nova Friburgo Health Institute, Fluminense Federal University (ISNF-UFF), Nova Friburgo-RJ, Brazil

Thiago H. Döring

Department of Exact Sciences and Education, Federal University of Santa Catarina, Blumenau-SC, Brazil

Fernando de C. da Silva

Applied Organic Synthesis Laboratory (LabSOA), Institute of Chemistry, Universidade Federal Fluminense, Niterói-RJ, Brazil

Vitor F. Ferreira

Department of Exact Sciences and Education, Federal University of Santa Catarina, Blumenau-SC, Brazil

Aldo S. de Oliveira

Department of Exact Sciences and Education, Federal University of Santa Catarina, Blumenau-SC, Brazil

Aislan C. R. F. Pascoal

Research Laboratory of Natural Products and Bioactive Molecules, Nova Friburgo Health Institute, Fluminense Federal University (ISNF-UFF), Nova Friburgo-RJ, Brazil

André L. S. Cruz

Physiopathology Laboratory, Institute of Medical Sciences, Multidisciplinary Center UFRJ, Federal University of Rio De Janeiro (UFRJ), Macaé-RJ, Brazil

Vanessa Nascimento

SupraSelen Laboratory, Department of Organic Chemistry, Institute of Chemistry, Federal University Fluminense, Niterói-RJ, Brazil