Obesity-Related Gut Microbiota Aggravates Alveolar Bone Destruction in Experimental Periodontitis through Elevation of Uric Acid
Keisuke Sato,
Kyoko Yamazaki,
Tamotsu Kato,
Yumiko Nakanishi,
Takahiro Tsuzuno,
Mai Yokoji-Takeuchi,
Miki Yamada-Hara,
Nobuaki Miura,
Shujiro Okuda,
Hiroshi Ohno,
Kazuhisa Yamazaki
Affiliations
Keisuke Sato
Research Unit for Oral-Systemic Connection, Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan
Kyoko Yamazaki
Research Unit for Oral-Systemic Connection, Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan
Tamotsu Kato
Laboratory for Intestinal Ecosystem, RIKEN Centre for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan
Yumiko Nakanishi
Laboratory for Intestinal Ecosystem, RIKEN Centre for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan
Takahiro Tsuzuno
Research Unit for Oral-Systemic Connection, Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan
Mai Yokoji-Takeuchi
Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan
Miki Yamada-Hara
Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan
Nobuaki Miura
Division of Bioinformatics, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan
Shujiro Okuda
Division of Bioinformatics, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan
Hiroshi Ohno
Laboratory for Intestinal Ecosystem, RIKEN Centre for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan
Research Unit for Oral-Systemic Connection, Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Chuo-ku, Niigata, Japan
Obesity is an epidemic health issue with a rapid increase worldwide. It increases the risk of various diseases, including periodontal disease, an oral chronic infectious disease.
