Biomedicines (Apr 2023)

Imaging Markers for Normal Pressure Hydrocephalus: An Overview

  • Efstratios-Stylianos Pyrgelis,
  • Georgios Velonakis,
  • Sokratis G. Papageorgiou,
  • Leonidas Stefanis,
  • Elisabeth Kapaki,
  • Vasilios C. Constantinides

DOI
https://doi.org/10.3390/biomedicines11051265
Journal volume & issue
Vol. 11, no. 5
p. 1265

Abstract

Read online

Idiopathic bormal pressure hydrocephalus (iNPH) is a neurological syndrome that clinically presents with Hakim’s triad, namely cognitive impairment, gait disturbances, and urinary incontinence. The fact that iNPH is potentially reversible makes its accurate and early diagnosis of paramount importance. Its main imaging characteristic is the dilation of the brain’s ventricular system and the imaging parameters are also included in its diagnostic criteria along with clinical data. There is a variety of different modalities used and a great number of imaging markers that have been described while assessing iNPH patients. The present literature review attempts to describe the most important of these imaging markers and to shed some light on their role in diagnosis, differential diagnosis, and possibly prognosis of this potentially reversible neurological syndrome.

Keywords