Metallo-β-Lactamase Producing Gram-Negative Bacteria Isolated from Chicken Meat in Bharatpur, Chitwan

Abstract

This study addresses the global public health concern of the rapid dissemination of acquired metallo-beta-lactamases (MBLs) in major Gram-negative pathogens. It focused on isolating MBL-producing Gram-negative bacteria in chicken meat from Bharatpur. Conducted from April to June 2023 at Balkumari College’s Microbiology laboratory in Bharatpur, Chitwan, the study analyzed 40 samples. The results revealed that E. coli, Citrobacter, Salmonella, Proteus, Shigella, and Klebsiella were prevalent, with varying degrees of multidrug resistance and MBL positivity. Notably, a significant proportion of the isolates exhibited MBL production, highlighting the need for vigilance and containment strategies in the face of this emerging threat.

Keywords

• <i>E. coli</i>
• prevalence
• multidrug resistance
• MBL