Communications Medicine (Sep 2022)
Early stimulated immune responses predict clinical disease severity in hospitalized COVID-19 patients
- Rebecka Svanberg,
- Cameron MacPherson,
- Adrian Zucco,
- Rudi Agius,
- Tereza Faitova,
- Michael Asger Andersen,
- Caspar da Cunha-Bang,
- Lars Klingen Gjærde,
- Maria Elizabeth Engel Møller,
- Patrick Terrence Brooks,
- Birgitte Lindegaard,
- Adin Sejdic,
- Anne Ortved Gang,
- Ditte Stampe Hersby,
- Christian Brieghel,
- Susanne Dam Nielsen,
- Daria Podlekareva,
- Annemette Hald,
- Jakob Thaning Bay,
- Hanne Marquart,
- Jens Lundgren,
- Anne-Mette Lebech,
- Marie Helleberg,
- Carsten Utoft Niemann,
- Sisse Rye Ostrowski
Affiliations
- Rebecka Svanberg
- Department of Hematology, Copenhagen University Hospital, Rigshospitalet
- Cameron MacPherson
- PERSIMUNE Center of Excellence, Copenhagen University Hospital, Rigshospitalet
- Adrian Zucco
- PERSIMUNE Center of Excellence, Copenhagen University Hospital, Rigshospitalet
- Rudi Agius
- Department of Hematology, Copenhagen University Hospital, Rigshospitalet
- Tereza Faitova
- Department of Hematology, Copenhagen University Hospital, Rigshospitalet
- Michael Asger Andersen
- Department of Hematology, Copenhagen University Hospital, Rigshospitalet
- Caspar da Cunha-Bang
- Department of Hematology, Copenhagen University Hospital, Rigshospitalet
- Lars Klingen Gjærde
- Department of Hematology, Copenhagen University Hospital, Rigshospitalet
- Maria Elizabeth Engel Møller
- Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet
- Patrick Terrence Brooks
- Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet
- Birgitte Lindegaard
- Department of Pulmonary and Infectious Diseases, Copenhagen University Hospital, Nordsjællands Hospital
- Adin Sejdic
- Department of Pulmonary and Infectious Diseases, Copenhagen University Hospital, Nordsjællands Hospital
- Anne Ortved Gang
- Department of Hematology, Copenhagen University Hospital, Rigshospitalet
- Ditte Stampe Hersby
- Department of Hematology, Copenhagen University Hospital, Rigshospitalet
- Christian Brieghel
- Department of Hematology, Copenhagen University Hospital, Rigshospitalet
- Susanne Dam Nielsen
- Department of Clinical Medicine, University of Copenhagen
- Daria Podlekareva
- Department of Respiratory Medicine, Bispebjerg Hospital
- Annemette Hald
- Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet
- Jakob Thaning Bay
- Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet
- Hanne Marquart
- Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet
- Jens Lundgren
- PERSIMUNE Center of Excellence, Copenhagen University Hospital, Rigshospitalet
- Anne-Mette Lebech
- Department of Clinical Medicine, University of Copenhagen
- Marie Helleberg
- PERSIMUNE Center of Excellence, Copenhagen University Hospital, Rigshospitalet
- Carsten Utoft Niemann
- Department of Hematology, Copenhagen University Hospital, Rigshospitalet
- Sisse Rye Ostrowski
- Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet
- DOI
- https://doi.org/10.1038/s43856-022-00178-5
- Journal volume & issue
-
Vol. 2,
no. 1
pp. 1 – 15
Abstract
Svanberg et al. longitudinally assess the immune response in patients with COVID-19. The authors report specific immune parameters associated with the development of severe disease.