Бюллетень сибирской медицины (Mar 2018)

The clinical observation of human papillomavirus positive breast tumor

  • M. K. Ibragimova,
  • M. M. Tsyganov,
  • N. A. Tarabanovskaya,
  • L. A. Tashireva,
  • I. V. Deryusheva,
  • V. M. Perelmuter,
  • E. M. Slonimskaya,
  • N. V. Litviakov

DOI
https://doi.org/10.20538/1682-0363-2018-1-232-238
Journal volume & issue
Vol. 17, no. 1
pp. 232 – 238

Abstract

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In this manuscript, a unique case of HPV16-positive breast cancer is examined. The presence of HPV infection in the tumor is confirmed by two independent methods (PCR and immunohistochemistry). It is shown that in the presence of adverse factors of prognosis (lymphogenous metastasis, high level of Ki67 expression, presence of chromotrypsis in the tumor, and high level of genetic instability), a patient with a HPV-positive breast tumor has more than 8-year disease-free survival.

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