Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva

Ting Xu; Wen Jin; Zhenzhen Wang; Haiyan Cheng; Xinhua Huang; Xiaoyu Guo; Ye Ying; Yiping Wu; Feng Wang; Ying Wen; Haifeng Yang

doi:10.3390/nano8030133

Nanomaterials (Feb 2018)

Electrospun CuO-Nanoparticles-Modified Polycaprolactone @Polypyrrole Fibers: An Application to Sensing Glucose in Saliva

Ting Xu,
Wen Jin,
Zhenzhen Wang,
Haiyan Cheng,
Xinhua Huang,
Xiaoyu Guo,
Ye Ying,
Yiping Wu,
Feng Wang,
Ying Wen,
Haifeng Yang

Affiliations

Ting Xu: The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China
Wen Jin: The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China
Zhenzhen Wang: The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China
Haiyan Cheng: The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China
Xinhua Huang: The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China
Xiaoyu Guo: The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China
Ye Ying: The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China
Yiping Wu: The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China
Feng Wang: The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China
Ying Wen: The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China
Haifeng Yang: The Education Ministry Key Lab of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors and Department of Chemistry, Shanghai Normal University, Shanghai 200234, China

DOI: https://doi.org/10.3390/nano8030133
Journal volume & issue: Vol. 8, no. 3
p. 133

Abstract

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A non-invasive method for detecting glucose is pursued by millions of diabetic patients to improve their personal management of blood glucose. In this work, a novel CuO nanoparticles (NPs) decorated polycaprolactone@polypyrrole fibers modified indium-tin oxide (denoted as CuO/PCL@PPy/ITO) electrode has been fabricated by electrospinning combined with the electrodeposition method for non-enzymatic detection of glucose in saliva fluid. The electrospun composite fibers exhibit high sensitivity for the glucose detection. The synergistic effect between CuO and PPy together with the unique three-dimensional net structure contributes the reliable selectivity, good test repeatability, large-scale production reproducibility in massive way, the reasonable stability and a high catalytic surface area to the sensor. Quantitative detection of glucose is determined in the linear range from 2 μM to 6 mM and the lowest detection limit is 0.8 μM. The CuO/PCL@PPy/ITO electrode shows potential for the non-invasive detection of salivary glucose.

Published in Nanomaterials

ISSN: 2079-4991 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry
Website: https://www.mdpi.com/journal/nanomaterials

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