Subcutaneous panniculitis-like T-cell lymphoma in children. Literature review and case reports

Abstract

Subcutaneous panniculitis-like T-cell lymphoma (SPTL) is a rare tumor from αβ mature cytotoxic T-lymphocytes, which primarily affects the subcutaneous adipose tissue and has morphological manifestations similar to panniculitis. SPTL frequency is less than 1 % of all NHL. It occurs in all age groups, but only 19–20 % are patients younger 20 years. Median age of patients is 35–36 years. To date are only a few cases in children described. In this article we described 3 SPTL cases in patients 1, 10 and 17 years old with typical clinical presentation and detailed analysis.

Keywords

• subcutaneous panniculitis-like T-cell lymphoma
• T-cell lymphoma immunophenotype
• lymphoproliferative diseases in children
• skin and subcutaneous adipose tissue lymphoma
• panniculitis