Nature Communications (Jul 2019)
Facile access to nitroarenes and nitroheteroarenes using N-nitrosaccharin
Abstract
Nitro(hetero) arenes are valuable intermediates in organic synthesis, therefore mild and safe methods to nitrate C-H bonds remain desirable. Here, the authors report a bench-stable, inexpensive, easy to synthesize and recyclable nitrating reagent based on saccharin, allowing for nitration of (hetero)arenes with broad scope.