Nature Communications (Sep 2020)

Interleukin-8 as a candidate for thymoma identification and recurrence surveillance

  • Shilin Gao,
  • Jiahao Jiang,
  • Chun Jin,
  • Jian Gao,
  • Dian Xiong,
  • Pengjie Yang,
  • Shuzhong Cui,
  • Wenhao Yang,
  • Qibin Leng,
  • Jihong Dong,
  • Gang Chen,
  • Junzhen Liu,
  • Li Wang,
  • Aiwu Ke,
  • Haikun Wang,
  • Jianyong Ding

DOI
https://doi.org/10.1038/s41467-020-18697-x
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 9

Abstract

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Imaging methods, such as CT or MRI, cannot provide accurate diagnosis between malignant thymomas and other thymic abnormalities. Here the authors show that the levels of IL-8 in circulating naive T cells are elevated in patients with thymoma compared with other thymic masses, proposing IL-8 as a candidate biomarker for thymoma diagnosis and recurrence surveillance.