94 The T cell antigen coupler (TAC) redirects T cell oncolysis while limiting tonic signaling to create a safer engineered T cell product with a higher threshold for activation

• Vivian Lau,
• Duane Moogk,
• Joanne Hammill,
• Jonathan Bramson,
• Arya Afsahi,
• Anna Dvorkin-Gheva,
• Ksenia Bezverbnaya

Affiliations

Vivian Lau

MMaster University, Hamilton, NY, Canada

Duane Moogk

Aff2 grid.137628.90000000121698901NYU School of Medicine New York NY USA

Joanne Hammill

Aff110 grid.25073.330000000419368227McMaster University Hamilton ON Canada

Jonathan Bramson

Aff110 grid.25073.330000000419368227McMaster University Hamilton ON Canada

Arya Afsahi

MMaster University, Hamilton, NY, Canada

Anna Dvorkin-Gheva

MMaster University, Hamilton, NY, Canada

Ksenia Bezverbnaya

MMaster University, Hamilton, NY, Canada