Central nervous system imaging in childhood Langerhans cell histiocytosis – a reference center analysis

Abstract

Background. The aim of our study was (1) to describe central nervous system (CNS) manifestations in children with Langerhans cell histiocytosis (LCH) based on images sent to a reference center and meeting minimum requirements and (2) to assess the inter-rater agreement of CNS-MRI results, which represents the overall reproducibility of this investigation.

Keywords

• langerhans cell histiocytosis
• child
• central nervous system
• magnetic resonance imaging