Juvenis Scientia (Apr 2021)
A NEW STEP-BY-STEP METHOD FOR ALLERGIC DERMATOSIS THERAPY
Abstract
Introduction. At the present stage, the search for new opportunities in the treatment of skin diseases is an urgent and demanded problem in practical medicine. Patients and methods. We examined 96 patients (men — 51 and women — 45) with allergic skin diseases, including 39 patients with atopic dermatitis (males — 20, females — 19) and 56 — with allergic dermatoses (men — 31 and women — 25). The patients' age ranged from 8 to 64 years. Among 96 patients, the main group consisted of 51 individuals (group I) (atopic dermatitis — 21, allergic dermatoses — 30) who received external therapy based on an innovative step-by-step method. Group II consisted of 45 patients (atopic dermatitis — 19, allergic dermatoses — 26) who received therapy according to the "Standards for Diagnosis and Treatment in Dermatovenereology and Medical Cosmetology" of the Ministry of Health of the Republic of Uzbekistan, 2019. The control group consisted of 36 healthy individuals. Results. The study showed that in the main group of patients, who received external therapy using a step-by-step innovative system (tonic "Fatiderm+", mud mask "Fatiderm+", moisturizing cream "Disderm"), the dynamics of resolution of the skin pathological process was significantly different from the control group, and the SCORAD index decreased 2.1 fold compared with the state before treatment (p<0.05). The use of the new external therapy contributed to a significant 43.5 fold decrease in the S. aureus colonization rate, as compared to the rate before treatment (p<0.05). Conclusion. Clinical and microbiological studies showed that the new innovative step-by-step external therapy has anti-inflammatory, regenerating, moisturizing, and bacteriostatic properties, and it can be recommended for widespread use as an external anti-inflammatory and moisturizing therapy in patients with allergic skin diseases.
