Jornal Brasileiro de Patologia e Medicina Laboratorial ()

Acute lymphocytic leukemia associated with toxoplasmosis: case report

  • Silmara Machado,
  • Leonardo R. G. Oliveira,
  • Beatriz M. Scalassara,
  • Karina G. Faria,
  • Lara E. F. O. Almeida

DOI
https://doi.org/10.5935/1676-2444.20200033
Journal volume & issue
Vol. 56

Abstract

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ABSTRACT Rare clinical case of acute lymphocytic leukemia (ALL) associated with toxoplasmosis affecting a 23-year-old male patient with progressive dyspnea. Chest computed tomography revealed expansive lesions indicating right supraclavicular fossa lymph node enlargement and right pleural effusion. Toxoplasmosis serology was performed: positive for immunoglobulin G [(IgG) 180.6] and positive for immunoglobulin M [(IgM) 0.98]. Therefore, treatment for the infection was initiated and immunohistochemistry of left cervical lymph node revealed ALL. Consequently, chemotherapy treatment was introduced at an oncology center. The diagnosis of toxoplasmosis allowed treatment to be administered, preventing the worsening of the condition caused by chemotherapy-induced immunosuppression.

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